Report on Clinical Application Analysis of 30 Cases of Beijing Anzhen Hospital of Capical University of Medical Sciences
Yang Wei Liu Yue Zhang Zhuo |
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Contemporary extensive survey research in epidemiology indicates that cardiovascular and cerebrovascular disease has been a kind of main common disease that causes various diseases and disability. Morbidity rate of the cardiovascular and cerebrovascular disease ranks first in a lot of urban and rural areas of China. Therefore, prevention and cure of this kind of disease especially cerebral apoplexy has become a key subject of hygiene work and medical research. At present, there are a lot of treatment methods to this kind of disease, and these methods have made certain curative effect. However, it is still a difficult problem that people face that discovers the treatment method which is safe and effective and simple and easy to do, especially recovery and class-III prevention after cerebral apoplexy. We have made good curative effects after we used King Tontown Cardiovascular and Cerebrovascular Therapeutic Instrument to make the treatment of acute stage and recovery stage for 30 cases. Now, we sum up the conclusion as follows:
I. Cases' selection
30 patients, including 20 male patiens, 10 female patients, with the age of 32-76 years old and average age of 62.4±9.5.
1. Cerebral infarction: 28 cases, course of disease: 3 days-4 years. Conditions of these patients are confirmed diagnosis by nerve department and CT.
2. Insufficient supply of blood of vertebral basilar artery: 2 cases, course of disease: 2 days-1 week. Main symptom: dizziness with nausea and vomiting, insufficient supply of blood of vertebral basilar artery indicated by TCD.In the above-mentioned 30 cases, 24 cases with high blood pressure, 2 cases with low blood pressure and 4 cases with normal blood pressure. In the 24 cases, blood pressure of 12 cases is controlled in the normal range after taking medicine, and blood pressure of another 12 cases is still high.
II. Therapeutic method
"Cardiovascular and Cerebrovascular Therapeutic Instrument" manufactured by King Tontown Medical Instruments Group Co., Ltd. is used. The instrument can output alternating electromagnetic wave. Patients lie down in the purpose-made insulating treatment bed quietly while treating. It takes 30-45 minutes each time, 1 time a day. 10 times is one course of treatment includes 10 times, generally it is effective in 2-3 courses of treatment in succession.
III.Observing index
Observe subjective symptom, language, muscle strength and action of patients with cerebrovascular disease. And measure blood pressure, blood fat, blood rheology, blood sugar and BUN.
IV. Determination of curative effect
Apparent effect: improvement of symptom and disappearing of hemiplegia.
Effective: improvement of symptom, increase of muscle strength, etc.
Noneffective: Without any change.
Result
(I) Clinical therapeutic effect (Table 1-1~1-2)
| Table 1-1 Clinical therapeutic effect |
| Disease |
Case Number |
Apparent Effect |
Effective |
Noneffective |
| Vertebral basilar artery |
2 |
2 |
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| Insufficient supply of blood |
|
|
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| Cerebral infarction |
28 |
4 |
19 |
5 |
We discovered by observing 30 cases that the total effective rate is up to 83.3% and noneffective rate is 16.7%; the effective rate treating cerebral infarction is up to 82.%, and noneffective cases mainly are the patients who have more than 2 years’ course of disease or have the disease come on for many times. Generally, it comes into play after 3-5 days’ treatment. Rank score of coloboma of nerve function before the treatment (rank score of apoplexy in Europe) is 76±16, and the rank score after the treatment is 84±14. The rank score of patients of cerebral infarction who have the similar rank score of coloboma of nerve function (before the treatment) but don’t use therapeutic instrument in the department is 79±16 after treating 10 days with the same drugs. P<0.05 is drawn through statistical treatment with remarkable difference (Table 1-2)
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| Table 1-2 Determination of treatment group and control group
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Before treatment |
After treatment |
P |
| Treatment group |
76±16 |
84±14 |
<0.05 |
| Control group |
75±17 |
79±16 |
<0.05 |
| P |
>0.05 |
<0.05 |
-- |
Table 2 Change of blood pressure before and after treating (n=12
| II. Change of blood pressure before and after treatment (Table 2) |
| Blood pressure |
Before treatment |
After treatment |
P |
| Systolic pressure (mmHg) |
167.1±8.9 |
144.6±13.2 |
<0.01 |
| Diastolic pressure (mmHg) |
91.8±10.3 |
84.2±9.3 |
<0.01 |
4 cases with normal blood pressure have no obvious effect before and after the treatment; blood pressure of 2 cases with low blood pressure 90/60mmHg) goes up after one course of treatment; 7 cases take less drugs or stop taking drugs in 12 cases with medical history of high blood pressure and good control of blood pressure after taking drugs after applying the therapeutic instrument.
III. Change of serum lipoprotein before and after treatment (Table 3)
| Table 3 Change of lipoprotein before and after treatment (n=30)
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| Lipoprotein |
Before treatment |
After treatment |
P |
| TG |
175.7±98.7 |
159.8±93.7 |
<0.01 |
| TC |
290.3±71.4 |
176.7±31.5 |
<0.01 |
| LDL-C |
148.2±27.4 |
125.2±23.7 |
<0.01 |
| HDL-C |
38.5±9.9 |
44.2±8.6 |
<0.01 |
IV. Change of blood rheology before and after treatment (Table 4)
| Table 4 Change of blood rheology before and after treatment (n=30) |
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High shear rate (mpa.s) |
Low shear rate (mpa.s) |
Viscosity of blood plasma (mpa.s) |
| Before treatment |
6.68V±1.15 |
11.84±3.18 |
2.20±0.27 |
| After treatment |
5.50±0.79 |
10.12±1.67 |
1.93±0.21 |
| P |
<0.01 |
<0.01 |
<0.01 |
Note: High shear rate is 230S-1, low shear rate is 23S-1.
Discussion
There are a lot of factors causing cerebrovascular disease. It is still difficult to reach in the present stage that attempts to dispel the pathogenic factors to prevent cerebrovascular disease, but incidence rate and death rate of cerebral apoplexy can be reduced remarkably if we give effective intervention to some dangerous factors that can be changed.
Arteriosclerosis is the most pathogeny of cerebral apoplexy. (1) Atherosclerosis: mainly involves large, medium and small arteries of the whole body, such as coronary artery, cerebral arteries and renal artery. In this course of development , abnormity of lipoprotein leads to a main crisis. Research proves that LDL-C participates in the Tableing of atherosclerosis, and HDL-C contributes to resisting the atherosclerosis and reducing the emergence of cerebrovascular disease. Result of the article indicates that King Tontown cardiovascular and cerebrovascular therapeutic instrument can reduce TG, TC and LDL-C and rise HDL-C, and have a significance for the prevention and cure of cardiovascular and cerebrovascular disease. (2) Minute arteriosclerosis with high blood pressure; continuous high blood pressure impels sedimentation of medium artery and intima of large venula and promotes atherosclerosis. High blood pressure makes small artery vessels of brain become small, cerebral vascular resistance increase, and cerebral blood flow decrease. The influence of cardiovascular and cerebrovascular therapeutic instrument on blood pressure has slowed down the development of atherosclerosis.
Blood rheology has close relation with emergence and development of cerebrovascular disease. Blood rheology plays an important role in the course of development of arteriosclerosis and thrombosis. TG directly participates in the Tableing of cholesterol and cholesterol fat, has closely relation with thrombosis, and has certain influence on the occurrence of cardiovascular and cerebrovascular embolized diseases, such as arteriosclerosis and coronary heart disease. TG can improve hematopexis and suppress dissolution of fibrin. The result shows that H-Vis and L-Vis can be all reduced after the treatment. This has something to do with the reduction of blood viscosity and change of nature of blood rheology after reducing TG, TC and LDL-C and rising HDL-C. Cardiovascular and cerebrovascular therapeutic instrument can produce the function of alternating electromagnetic field, which makes tissues and organs of pathological changes produce the change of physicochemical property, such as internal particle migration, change of internal and external chemical composition in the histiocyte and change of ion concentration in and out of the biological membrane, and thus produces physiological therapeutic action. All of these are main factors influencing blood rheology. The reduction of blood viscosity also makes vascular resistance reduced and thus reduces blood pressure.
Cardiovascular and cerebrovascular therapeutic instrument can adjust the function of autonomic nervous system, change elasticity of blood vessels of the whole body, reduce peripheral resistance and overhigh blood pressure and expand cerebral arteries effectively; it can rise low blood pressure, increase cerebral blood flow and improve cerebral blood supply. In these 30 cases, insomnia and the symptom of dream-disturbed sleep of quite a few of them have gotten remarkable improvement.
In therapeutic reaction and side effect, part patients produce the increase of blood pressure, which generally occurs in 3-5 days after the treatment and can disappear automatically after continuing treating.
In sum, “King Tontown Cardiovascular and Cerebrovascular Therapeutic Instrument” can effectively improve lipoprotein, reduce blood viscosity, change the nature of blood rheology, impel the expansion of blood vessel in the brain tissue and increase of brain blood stream, alleviate angiospasm and improve blood pressure. It helps the Tableing of collateral circulation to improve ischemic state of brain tissue and metabolism and promote regenerating restoration of brain tissue to recover the function. It has made satisfactory result in clinical application and has no obvious side effect. It has a wide application prospect to the rehabilitation of the above-mentioned diseases.
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