The Affiliated
Gulou Branch, Hospital of Nanjing University Clinic Application for Therapy of
Ischemic Cerebral Infarction
Tang Guoqiang and Han Zhen
This paper published in China Quantum Medicine and Health, 5th Edition,
October 2004.
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[Abstract] Objective: to discuss the therapeutic effect of the alternating
electromagnetic field produced by Cardio-/Cerebrovascular Therapeutic
Instrument(hereafter called as “CCTI”) to cure the ischemic cerebral
infarction. Method: While taking drugs, 48
ischemic-cerebral-infarction-conformed cases use CCTI for treatment, 1time per
day and 15 times as one course of treatment. The patients are required to
continue using the CCTI for 2～3 courses. We compared them with those 47 cases
who only took medicine. Results: After two courses of treatment, the CCTI group
made good in the restoring of nervous function damage, and there was great
changes in blood rheology index before and after treatment. Conclusion: CCTI
can effectively change the blood rheology index and improve the clinic
symptoms. Using CCTI is an effective method to cure ischemic cerebral
infarction.
[Key Words] CCTI, Alternating magnetic field, ischemic cerebral infarction,
blood rheology check
[CLC No.]R743.33 [DOC Code]B
[Paper No.]1007-5496 （1999）11-1390-02
Ischemic cerebral infarction is a kind of cerebrovascular disease caused by the
necrosis and malacia of brain tissue due to ischemia and anoxia which is
resulted from the failure of brain blood supply. In recent two years, our
department has been using “CCTI” to cure this diseases and made a good result
through clinic observations. Now, we hereby report as below:
I. Material and Method
1.1 General Material: According to the diagnose criteria amended in the
National Conference on Cerebrovascular Diseases held by Chinese Medical
Association [1], and through Head CT or MRI test, 95 cases were confirmed with
the cerebral infarction, including 58 male cases and 37 female cases aged from
41 to 49 years old averaged at 58.6±6.7 years old. After the patients were
admitted into this hospital, we randomly divided them into two groups: 48 cases
in CCTI Group and 47 cases in Compared Group. Among 95 patients, 35 cases has
less than one month of illness course (non-acute period), 42 cases for 1-6
months and 18 case for more than 6 months, 13 cases with disease focus in top
forehead, 62 cases with focus in basilar node area, 9 cases in brain stem and
11 cases in cerebellum. Scores for damage of nerve functions: Light: 36 cases
between 0～15 scores, Middle: 39 cases between 16～30 scores, Heavy: 20 cases
between 31～45 scores. There were 55 cases with high blood pressure, 37 cases
with diabetes and 32 cases with coronary heart disease. The two groups were
basically same with each other in cases, illness conditions, age, gender and
damage of nerve functions. With the statistics processing, there was no obvious
difference (P＞0.05).
1.2 Method of Therapy: Both groups were injected with low molecular dextran and
Mailuoning injection, and took Nimodipime, dissolved Aspirin and Piracetan
orally. With above medicines, CCTI group also use CCTI (made by King Tontown
Medical Instrument Co., Ltd.) for treatment. Input 220V voltage with 50 Hz
frequency, CCTI will output alternating electromagnetic wave. Let the patient
sit on the therapeutic chair, 30 minutes per time and 1 time per day. 15 days
was one course of treatment. If necessary, the patient could continue treatment
for 2 courses. Before and after treatment, we carried out the scoring on the
damage of nerve function and observation on the effect and the blood rheology
index as well.
2. Results
2.1 Criteria for Assessment of Therapeutic Effect: The assessment was carried
out after 30 days (two courses) on the two groups. Basically Cured: symptoms
and signs disappeared, and the patients can serve themselves in daily life;
Apparent Effect: the muscle strength of hemiplegic side body reached Grade IV,
and the patients can serve themselves in part of daily life; Effective: the
muscle strength of hemiplegic side body, speaking obviously restored and
improved; Ineffective: there is no change of symptoms and signs before and
after treatment.
2.2 Results: Effect Comparison between two groups and Changes of Blood Rheology
Index (See Table 1-2)
| Table 1 Blood Pressure Change Before and
After Treatment（X±S） |
| Group |
Case |
Basically Cured |
Apparent Effect |
Effectice |
Ineffective |
Effectivenss(%) |
| CCTI Group |
48 |
14 |
16 |
10 |
8 |
83.3 |
| Compared Group |
47 |
8 |
12 |
12 |
15 |
68.1 |
There are great difference between CCTI Group and the Compared Group(P＜0.05).
Changes of Main Blood Rheology Index of CCTI Group before and after Treatment
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| Table 2 Changes of Main Blood Rheology
of the Two Groups before and After Treatment (xs) |
| Item |
CCTI Group |
Compared Group |
| |
Pre-treatment |
Post-treatment |
Pre-treatment |
Post-treatment |
| Whole Blood Viscosity, low shear(mpa.s) |
8.92±0.32 |
7.41±0.51 |
8.89±0.75 |
7.73±0.87 |
| Whole Blood Viscosity, high shear(mpa.s) |
5.43±1.12 |
4.32±0.58 |
5.16±1.21 |
4.89±0.72 |
| Plasma Viscosity(mpa.s) |
1.92±0.15 |
1.64±0.10 |
1.88±0.16 |
1.81±0.02 |
From the tables, we can see that there is great improvement by using CCTI
(P0.01）The difference of the main blood rheology index between the two groups
is obvious very much (P＜0.05).
3. Discussion At present, there are many drugs for
ischemic cerebral infarction, but because of the long-lasting curative period,
the effect is not satisfying. Therefore, we can get a better result by taking
drugs along with the electromagnetic effect.
“CCTI” works vis the alternating electromagnetic field produced by itself to
expand the blood vessels and speed the blood flow. It can activate the blood
circulation and dissipate the blood stasis and improve the microcirculation.
When cerebral infarction happens, part of brain blood flow rate decreases due
to the insufficient blood flow, flow stoppage and cerebral edema.The long-term
lacking of blood supply and oxygen can lead to the crack-up of brain cells and
abnormal activities of cerebral electricity. In addition, the blood rheology
has a close relationship with the occurrence and development of the cerebral
infarction. The increase of blood viscosity can lead to the failure of
microcirculation and reduce the blood supply to our brain, which can worsen the
illness due to the lacking of oxygen. Therefore, a high blood viscosity is the
key for many pathological courses, so it is very important to control and
improve the blood viscosity.
At present, it is known that the main factors for the blood viscosity are the
deformability and cohesion of the red blood cells, density of blood cells and
the plasma concentration[2]. With the action of magnetic field, the glomeration
of red blood cells can be depolymerized, and the deformability is strengthened,
thus to reduce the blood viscosity and improve the characteristics of blood
rheology [3] and speed the blood circulation and better the cerebral infarction
conditions. Meanwhile, CCTI also can effectively improve the lipoprotein and
its subcomponent and has certain effects on the relief and prevention of
cardio-/cerebrovascular diseases.
Through clinic observation, the patients of CCTI Group improved their muscle
strength, spoke much more clearly than before with fast recovery of memory and
the relief of headache and dizziness. For certain patients, CCTI can help them
reduce the blood pressure. Therefore, the therapy by using CCTI is reliable and
no side effects found. CCTI is an effective way to increase the curative ratio
of ischemic cerebral infarction.
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